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Anhydrotetracycline hydrochloride, Thermo Scientific™
Anhydrotetracycline hydrochloride, CAS # 13803-65-1, is a tetracycline derivative showing antibacterial activity commonly used to control tetracycline-dependent gene expression systems in bacteria.
Brand: Thermo Scientific Alfa Aesar J66688.MA
| Quantity | 10mg |
|---|
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Description
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
General Description
• Anhydrotetracycline hydrochloride is a degradation product derived from tetracycline hydrochloride. It acts as an effector of tetracycline-dependent gene expression in bacterial expression systems. In this system the transcription of genes is reversibly turned on/off in the presence of several compounds including, anhydrotetracycline hydrochloride.
• This compound poorly binds to the 30S ribosomal subunit compared with its precursor, tetracycline.
Applications
• Anhydrotetracycline hydrochloride is commonly used in all fields of biology for control of transcription or translation processes
• This compound has been used in laboratory experiments and shows lower antibacterial activity against Escherichia coli compared with tetracycline.
Chemical Identifiers
| 13803-65-1 | |
| 446.88 | |
| FFZXKJVSZDKEMY-XGRJIHFXNA-N | |
| hydrogen (2Z)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-11,12a-dihydroxy-6-methyl-1,2,3,4,4a,5,12,12a-octahydrotetracene-1,3,12-trione chloride |
| C22H23ClN2O6 | |
| MFCD00151453 | |
| 54710409 | |
| [H+].[Cl-].CN(C)C1C2CC3=C(C(O)=C4C=CC=CC4=C3C)C(=O)C2(O)C(=O)\C(=C(\N)O)C1=O |
Specifications
| 13803-65-1 | |
| 10mg | |
| C22H23ClN2O6 | |
| 4228856 | |
| FFZXKJVSZDKEMY-XGRJIHFXNA-N | |
| hydrogen (2Z)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-11,12a-dihydroxy-6-methyl-1,2,3,4,4a,5,12,12a-octahydrotetracene-1,3,12-trione chloride | |
| 54710409 | |
| Anhydrotetracycline hydrochloride |
| Yellow | |
| Moisture sensitive | |
| MFCD00151453 | |
| Soluble in ethanol, DMSO, or DMF | |
| [H+].[Cl-].CN(C)C1C2CC3=C(C(O)=C4C=CC=CC4=C3C)C(=O)C2(O)C(=O)\C(=C(\N)O)C1=O | |
| 446.88 | |
| 462.88 |
Safety and Handling
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
Supplemental information
- Anhydrotetracycline hydrochloride
Signal Word
- Warning
Hazard Category
- Serious eye damage/eye irritation Category 2
- Reproductive toxicity Category 2
Hazard Statement
- H319-Causes serious eye irritation.
- H361d-Suspected of damaging the unborn child.
Precautionary Statement
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P308+P313-IF exposed or concerned: Get medical advice/attention.
Supplemental information
- MIXTURE LIST-Contains : Anhydrotetracyclinehydrochloride
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