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Invitrogen™ Human AMPK alpha-1/beta-2/gamma-2, GST Tag, His Tag Recombinant Protein
Human AMPK alpha-1/beta-2/gamma-2, GST Tag, His Tag Recombinant Protein
Brand: Invitrogen™ A33551
This item is not returnable.
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Description
AMPK (A1/B2/G2) serine/threonine kinase or AMP-activated protein kinase (AMPK) exhibits a key role as a master regulator of cellular energy homeostasis. AMPK exists as a heterotrimeric complex composed of a catalytic alpha subunit and regulatory beta and gamma subunits. Binding of AMP to the gamma subunit allosterically activates the complex. AMPK is activated in response to stresses that deplete cellular ATP (low glucose, hypoxia and ischemia) and via signaling pathways in response to adiponectin, leptin and CAMKK beta.- Validated for use with the Z’-LYTE™ assay
- Available in multiple pack sizes for convenient use
Specifications
| PRKAA1: NP_006242.4, PRKAB2: NP_005390.1, PRKAG2: NP_001035723.1 | |
| 90.3/56.6/85.6 kDa | |
| CAMKL Kinase Family | |
| Human | |
| GST Tag, His Tag | |
| Dry Ice | |
| Full Length, Recombinant, Active |
| Kinase Assay | |
| 100 μg | |
| Full Length | |
| Recombinant | |
| Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. | |
| Insect | |
| Liquid |