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Amitriptyline hydrochloride, MedChemExpress

Product Code. 16450978
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5 g
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16450978 5 g 5g
16432219 1 g 1g
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Product Code. 16450978 Supplier Medchem Express Supplier No. HYB0527A
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Estimated Shipment: 22-09-2026
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Description

MedChemExpress Amitriptyline hydrochloride is an inhibitor of serotonin reuptake transporter (SERT) and noradrenaline reuptake transporter (NET), with Kis of 3.45 nM and 13.3 nM for human SERT and NET, respectively.

Amitriptyline hydrochloride also weakly binds to dopamine reuptake transporter (DAT) with a Ki of 2.58 μM. Amitriptyline hydrochloride also inhibits adrenergic, muscarinic, histamine and 5-HT receptors. Amitriptyline hydrochloride is a TrkA and TrkB receptors agonist with potent neurotrophic activity. Amitriptyline hydrochloride has antidepressant activity.

Specifications

Chemical Name or Material Amitriptyline hydrochloride
Physical Form Solid
CAS 549-18-8
Color White
Quantity 5 g
Purity Grade Notes Research
Molecular Formula C20H24ClN
For Use With (Application) Neuroscience-Neurodegeneration
Solubility Information DMSO : ≥ 100 mg/mL (318.61 mM) ∣H2O : ≥ 50 mg/mL (159.31 mM)
SMILES CN(C)CC/C=C1C2=CC=CC=C2CCC3=C\1C=CC=C3.Cl
Molecular Weight (g/mol) 313.86
Formula Weight 313.86
Percent Purity 99.56%
Grade Research
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Research purposes only

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