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Amiloride hydrochloride dihydrate, Thermo Scientific™
Sodium channel blocker
960.00 NOK - 3000.00 NOK
Chemical Identifiers
| CAS | 17440-83-4 |
|---|---|
| Molecular Formula | C6H13Cl2N7O3 |
| Molecular Weight (g/mol) | 302.116 |
| MDL Number | MFCD00058197 |
| InChI Key | LTKVFMLMEYCWMK-UHFFFAOYSA-N |
| Synonym | amiloride hydrochloride dihydrate, modamide, nirulid, amiloride hcl, amiloride hcl dihydrate, amilorid hydrochlorid-2-wasser, unii-fzj37245uc, amiloride hydrochloride usan:usp, amiloride dihydrate hydrochloride, n-amidino-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride dihydrate |
| PubChem CID | 68540 |
| ChEBI | CHEBI:2640 |
| IUPAC Name | 3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide;dihydrate;hydrochloride |
| SMILES | C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N.O.O.Cl |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
15414599
|
Thermo Scientific Alfa Aesar
J62168.03 |
1g |
960.00 NOK
1g |
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|
15424599
|
Thermo Scientific Alfa Aesar
J62168.06 |
5g |
3000.00 NOK
5g |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
ApplicationsAmiloride hydrochloride dihydrate is used as a calcium channel and sodium channel protein inhibitor. It reduces electrical potential across tubular epithelium, inhibits angiogenesis and inhibits capillary morphogenesis completely and reversibly at approximately 130 μM. Amiloride • HCl is an inhibitor of Sodium/Potassium-ATPase Protein. Defines the I2A-amiloride sensitive and I2B-amiloride insensitive imidazoline binding Blocks TRPP3, acid sensing- (ASIC) and mechanogated membrane-ion channels, as well as the Na+/H+ exchanger. Also inhibits urokinase-type plasminogen activator (uPA); has no effect on tissue-type plasminogen activator.
Solubility
Soluble in water at 50mg/ml
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.
Chemical Identifiers
| 17440-83-4 | |
| 302.116 | |
| LTKVFMLMEYCWMK-UHFFFAOYSA-N | |
| 68540 | |
| 3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide;dihydrate;hydrochloride |
| C6H13Cl2N7O3 | |
| MFCD00058197 | |
| amiloride hydrochloride dihydrate, modamide, nirulid, amiloride hcl, amiloride hcl dihydrate, amilorid hydrochlorid-2-wasser, unii-fzj37245uc, amiloride hydrochloride usan:usp, amiloride dihydrate hydrochloride, n-amidino-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride dihydrate | |
| CHEBI:2640 | |
| C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N.O.O.Cl |
Specifications
| 17440-83-4 | |
| MFCD00058197 | |
| 14,406 | |
| Soluble in water at 50mg/ml | |
| C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N.O.O.Cl | |
| 302.116 | |
| CHEBI:2640 | |
| Amiloride hydrochloride dihydrate |
| C6H13Cl2N7O3 | |
| UN2811 | |
| amiloride hydrochloride dihydrate, modamide, nirulid, amiloride hcl, amiloride hcl dihydrate, amilorid hydrochlorid-2-wasser, unii-fzj37245uc, amiloride hydrochloride usan:usp, amiloride dihydrate hydrochloride, n-amidino-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride dihydrate | |
| LTKVFMLMEYCWMK-UHFFFAOYSA-N | |
| 3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide;dihydrate;hydrochloride | |
| 68540 | |
| 266.09 |
Safety and Handling
GHS H Statement
H301
Toxic if swallowed.
P264b-P270-P301+P310-P330-P501c
H301
missing translation for 'dotInformation' : Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
missing translation for 'einecsNumber' : 217-958-2
missing translation for 'rtecsNumber' : UQ2275500
missing translation for 'tsca' : No
Recommended Storage : Ambient temperatures
RUO – Research Use Only
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