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Amikacin disulfate

Product Code. 15416019
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Product Code. 15416019 Supplier Thermo Scientific Alfa Aesar Supplier No. J63862.14
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Description

An aminoglycoside antibiotic derived from Kanamycin A | CAS: 39831-55-5 | C22H47N5O21S2 | 781.75 g/mol

Amikacin disulfate is used as an aminoglycoside antibiotic derived from Kanamycin A, used for treating infections with multidrug resistant Gram negative bacteria such as Pseudomonas aeruginosa, Acinetobacter, and Enterobacter. It is commonly used in the treatment of drug-resistant mycobacteria. It is used to study organism-directed delivery of antibiotics as well as drug resistance.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Amikacin disulfate is used as an aminoglycoside antibiotic derived from Kanamycin A, used for treating infections with multidrug resistant Gram negative bacteria such as Pseudomonas aeruginosa, Acinetobacter, and Enterobacter. It is commonly used in the treatment of drug-resistant mycobacteria. It is used to study organism-directed delivery of antibiotics as well as drug resistance.

Solubility
Soluble in water at 50mg/ml with warming

Notes
Potency: 674-786 micrograms per mg
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 39831-55-5
Molecular Formula C22H47N5O21S2
Molecular Weight (g/mol) 781.75
MDL Number MFCD00167475,MFCD00167475
InChI Key FXKSEJFHKVNEFI-GCZBSULCSA-N
PubChem CID 134129615
IUPAC Name (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4-{[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-3-hydroxycyclohexyl]-2-hydroxybutanamide; bis(sulfuric acid)
SMILES OS(O)(=O)=O.OS(O)(=O)=O.NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](N)[C@H]1O

Specifications

Type Amikacin Disulfate
Physical Form Powder
Melting Point 220°C to 230°C
Color White
Quantity 25 g
Beilstein 6172633
Merck Index 14,405
Solubility Information Soluble in water at 50mg/ml with warming
Formula Weight 781.77
Chemical Name or Material Amikacin disulfate

Safety and Handling

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Product Identifier
  • Amikacin disulfate
 Signal Word
  • Danger
 Hazard Category
  • Serious eye damage/eye irritation Category 1
  • Skin sensitiser Category 1
  • Specific target organ toxicity Category 1
 Hazard Statement
  • H317-May cause an allergic skin reaction.
  • H318-Causes serious eye damage.
  • H372-Causes damage to organs.
 Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P310-Immediately call a POISON CENTER/doctor/.
 Supplemental information
  • MIXTURE LIST-Contain: Amikacin sulfate
SDS

RUO – Research Use Only

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