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  6. Alpha E catenin Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Alpha E catenin Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. p-7204653 Shop All Proteintech Products
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Quantity:
150 μL
20 μL
Unit Size:
150µL
20µL
Product Code. Quantity unitSize
16870754 20 μL 20µL
16860754 150 μL 150µL
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Product Code. 16870754

Brand: Proteintech 128311AP20UL

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Description

Rabbit Polyclonal Antibody

Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherence junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. May play a crucial role in cell differentiation.

Specifications

Antigen Alpha E catenin
Applications Immunoprecipitation, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Flow Cytometry
Classification Polyclonal
Concentration 0.41 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene CTNNA1
Gene Accession No. P26231, P35221
Gene Alias alpha catenin, Alpha E catenin, Cadherin associated protein, CAP102, Catenin alpha 1, CTNNA1, alpha-catenin, alpha-E-catenin, alphaE-catenin
Gene Symbols Ctnna1
Host Species Rabbit
Immunogen Alpha E catenin Fusion Protein Ag3565
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12385, 1495, 307505
Target Species Human, Rat, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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