missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organoheterocyclic compounds
  6. Pyrroles
  7. Almonertinib hydrochloride, MedChemExpress

Almonertinib hydrochloride, MedChemExpress

Product Code. 16495536
Encompass_Preferred
Change view
Click to view available options
Quantity:
5 mg
10 mg
25 mg
50 mg
100 mg
Unit Size:
100mg
10mg
25mg
50mg
5mg
Product Code. Quantity unitSize
16495536 100 mg 100mg
16447427 5 mg 5mg
16421007 50 mg 50mg
16414718 10 mg 10mg
16403216 25 mg 25mg
5 options
This item is not returnable. View return policy

Product Code. 16495536

Brand: Medchem Express HY112823B

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

MedChemExpress Almonertinib (HS-10296) hydrochloride is an orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor with high selectivity for EGFR-sensitizing and T790M resistance mutations.

Almonertinib hydrochloride shows great inhibitory activity against T790M, T790M/L858R and T790M/Del19 (IC50: 0.37, 0.29 and 0.21 nM, respectively), and is less effective against wild type (3.39 nM). Almonertinib hydrochloride is used for the research of the non-small cell lung cancer.

Specifications

Chemical Name or Material Almonertinib hydrochloride
CAS 2134096-03-8
Color Off-White
Purity Grade Notes Research
Molecular Formula C30H36ClN7O2
Quantity 100 mg
Synonym HS-10296 hydrochloride
Solubility Information DMSO : 83.33 mg/mL (148.25 mM; Need ultrasonic)
SMILES COC(C=C(N(C)CCN(C)C)C(NC(C=C)=O)=C1)=C1NC2=NC(C3=CN(C4CC4)C5=C3C=CC=C5)=CC=N2.[H]Cl
Molecular Weight (g/mol) 562.11
Formula Weight 562.11
Percent Purity 98.03%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
Show More Show Less

Research purposes only

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.