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Invitrogen™ Human ALK, GST Tag Recombinant Protein
Anaplastic Lymphoma Receptor Tyrosine Kinase (ALK) belongs to the insulin receptor superfamily.
Brand: Invitrogen™ PV3867
Additional Details : CAS Number : 9048-46-8 Weight : 0.00900kg
Description
ALK is vital for brain development. Mutations, rearrangements, and amplifications in the ALK gene have been found in tumors, including anaplastic large cell lymphoma, neurblastoma, and non-small cell lung cancer. Chromosomal rearrangement is the most common genetic alteration.
Specifications
| NP_004295, NP_004295.2, J1461V | |
| 114294, 238, 238 | |
| 10μg | |
| ALK Kinase Family | |
| Human | |
| Kinases & Inhibitors | |
| Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical europium phospho-specific activity, Biochemical binding/kinetic | |
| Dry Ice | |
| ALK | |
| Baculovirus | |
| Recombinant, Active, Cytoplasmic | |
| Kinases & Inhibitors |
| Kinase Assay | |
| 89.9 kDa, 90 kDa | |
| CD246, NBLST3 | |
| aa 1058-1620 | |
| Recombinant | |
| Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% glycerol Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws. |
|
| Tyrosine Kinases | |
| LanthaScreen™ Antibody, LanthaScreen™ Substrate, Z'-LYTE™, Omnia™ Bulk Substrate | |
| anaplastic lymphoma receptor tyrosine kinase | |
| Kinases & Inhibitors | |
| Liquid | |
| Signal Transduction |