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Aldehyde oxidase Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 19495-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16889014

  • 3468.15 NOK / 150µL
Estimated Shipment: 13-12-2022
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Description

Description

AOX1 (Aldehyde oxidase 1) is a 1338 amino acid cytoplasmic protein that catalyzes the oxidation of a variety of aldehydes, leading to the production of hydrogen peroxide. Under certain conditions, AOX1 can catalyze the formation of the superoxide free radical. Defects in oxygen radical metabolism have been linked to the pathogenesis of amyotrophic lateral sclerosis (ALS), an autosomal domit neurodegenerative disorder characterized by the death of motor neurons in the spinal cord, brain and brainstem. Significantly, AOX1 is highly expressed in the ventral horn of the spinal cord and the gene that encodes AOX1 is located in a chromosomal region that is frequently found to be implicated in ALS2. This evidence suggests that AOX1 is a candidate gene for ALS2.
Specifications

Specifications

Aldehyde oxidase
Polyclonal
Unconjugated
AOX1
Aldehyde oxidase, aldehyde oxidase 1, AO, AOH1, AOX1
Rabbit
Antigen Affinity Chromatography
RUO
11761, 316, 54349
-20°C
Liquid
Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry
0.43 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O54754, Q06278, Q9Z0U5
AOX1
Peptide
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
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