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AIFM3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 14778-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16893584

  • 3468.15 NOK / 150µL
Estimated Shipment: 20-12-2022
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Description

Description

Apoptosis, also known as programmed cell death, plays major roles in development and normal tissue turnover in addition to tumor formation. Recently a protein similar to the apoptosis-inducing factor (AIF) was cloned and designated AIFL (also known as AIFM3). AIFM3 is expressed ubiquitously and is predomitly localized to the inner membranes of mitochondria. Unlike AIF, AIFM3 does not translocate to the nucleus upon induction of apoptosis. However, overexpression of AIFM3, like AIF, induced cytochrome c release from the mitochondria, cleavage of caspase 3, and ultimately apoptosis, indicating AIFM3 induces apoptosis through caspase activation. Multiple isoforms of AIFM3 are known to exist.
Specifications

Specifications

AIFM3
Polyclonal
Unconjugated
AIFM3
AIFL, AIFM3, Apoptosis inducing factor 3
Rabbit
Antigen Affinity Chromatography
RUO
150209, 303786, 72168
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin)
0.29 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q3TY86, Q96NN9
Aifm3
AIFM3 Fusion Protein Ag6278
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
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