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  6. Adenylosuccinate lyase Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Adenylosuccinate lyase Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16824364 Shop All Proteintech Products
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Quantity:
150 μL
20 μL
Unit Size:
150µL
20µL
Product Code. Quantity unitSize
16824364 150 μL 150µL
16834364 20 μL 20µL
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Product Code. 16824364

Brand: Proteintech 152641AP150UL

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Description

Rabbit Polyclonal Antibody

ADSL (adenylosuccinate lyase), also known as AMPS, ASL or ASASE, is a 484 amino acid protein that is involved in both purine biosynthesis and in the formation of adenosine monophosphate (AMP) from inosine monophosphate. Expressed ubiquitously, ADSL catalyzes two key reactions in AMP biosynthesis, namely the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and the subsequent removal of fumarate from adenylosuccinate to yield AMP. Defects in the gene encoding ADSL are the cause of adenylosuccinase deficiency (ADSL deficiency), an autosomal recessive disorder characterized by epilepsy, growth retardation and muscular wasting. Multiple isoforms of ADSL exist due to alternative splicing events.

Specifications

Antigen Adenylosuccinate lyase
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.22 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ADSL
Gene Accession No. P30566, P54822
Gene Alias Adenylosuccinase, adenylosuccinate lyase, ADSL, AMPS, ASASE, ASL
Gene Symbols ADSL
Host Species Rabbit
Immunogen Adenylosuccinate lyase Fusion Protein Ag7332
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11564, 158, 315150
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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