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ACAP1 Mouse anti-Human, Clone: 1B4C9, Proteintech

Mouse Monoclonal Antibody

1611.84 NOK - 4593.76 NOK

Specifications

Antigen ACAP1
Clone 1B4C9
Concentration 1 mg/mL
Applications Western Blot, Immunohistochemistry (Paraffin)
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16888615
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Proteintech
66596-1-IG-20UL
20 μL
1611.84 NOK
20µL
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Estimated Shipment: 17-04-2024
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16878615
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Proteintech
66596-1-IG-150UL
150 μL
4593.76 NOK
150µL
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Estimated Shipment: 17-04-2024
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Description

Description

ACAP1, also known as Centaurin-beta-1 (CENTB1), is a 740 amino acid containing transport carrier belonging to the Centaurin family with three ANK repeats, an Arf-GAP domain, a BAR domain and a PH domain that binds to phospholipids. ACAP1, a GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6), is required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. It mediates CENTB1-binding to phosphatidylinositol 3,5-bisphosphate (PIP2) or phosphatidylinositol 3,4,5-trisphosphate (PIP3) containing membranes. Along with ACAP2, ACAP1 is recruited to platelet-derived growth factor (PDGF) induced dorsal membrane ruffles in NIH 3T3 mouse fibroblasts, while over expression inhibited ruffle formation. It is widely expressed in most tissues with high expression in lung and spleen and low expression in heart, kidney, liver and pancreas.
Specifications

Specifications

ACAP1
1 mg/mL
Monoclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
ACAP1, Centaurin beta 1, CENTB1, Cnt b1, KIAA0050
ACAP1
IgG1
Protein G
Antibody
1B4C9
Western Blot, Immunohistochemistry (Paraffin)
Unconjugated
Mouse
Human
Q15027
9744
ACAP1 Fusion Protein Ag14254
Primary
-20°C
ACAP1
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