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Description
Immunogen sequence: AEWLGLLGDE QVPQAESILD ALSKHLVMKL SYGPEEKDMI VMRDSFGIRH PSGHLEHKTI DLVAYGDING FSAMAKTVGL PTAMAAKMLL DGEIGAKGLM GPFSKEIYGP ILERIKA Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.
AASS is a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in the gene encoding this protein are associated with familial hyperlysinemia.
Specifications
Specifications
| Antigen | AASS |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | AASS |
| Gene Accession No. | Q9UDR5 |
| Gene Alias | AASS; aass {ECO:0000312; alpha-aminoadipate semialdehyde synthase; alpha-aminoadipic semialdehyde synthase, mitochondrial; aminoadipate-semialdehyde synthase; aminoadipic semialdehyde synthase; EMBL:AAI28772.1}; LKR; LKR/SDH; LKRSDH; LOR; LOR/SDH; Lorsdh; Lysine ketoglutarate reductase; lysine oxoglutarate reductase; lysine-2-oxoglutarate reductase; lysine-ketoglutarate reductase /saccharopine dehydrogenase; saccharopine dehydrogenase; SDH |
| Gene Symbols | AASS |
| Show More |
Product Title
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