missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Benzenoids
  6. Benzene and substituted derivatives
  7. Phenoxy compounds
  8. A-366, MedChemExpress

A-366, MedChemExpress

Product Code. 16411467
Encompass_Preferred
Change view
Click to view available options
Quantity:
5 mg
10 mg
50 mg
Unit Size:
10mg
50mg
5mg
3 product options available for selection
Product selection table with 3 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
16411467 50 mg 50mg
16407977 5 mg 5mg
16405258 10 mg 10mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 3 options available.
3 options
This item is not returnable. View return policy
Product Code. 16411467 Supplier Medchem Express Supplier No. HY12583

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

MedChemExpress A-366 is a potent, highly selective, peptide-competitive histone methyltransferase G9a inhibitor with IC50s of 3.3 and 38 nM for G9a and GLP (EHMT1), respectively.

A-366 shows >1000-fold selectivity over 21 other methyltransferases. A-366 is also a potent, nanomolar inhibitor of the Spindlin1-H3K4me3-interaction (IC50=182.6 nM). A-366 displays high affinity at human histamine H3 receptor (Ki=17 nM) and shows subtype selectivity among subsets of the histaminergic and dopaminergic receptor families.

Specifications

Chemical Name or Material A-366
CAS 1527503-11-2
Color Yellow
Purity Grade Notes Research
Molecular Formula C19H27N3O2
Quantity 50 mg
Solubility Information DMSO : 50 mg/mL (151.77 mM; Need ultrasonic)
SMILES COC1=CC2=C(N=C(N)C23CCC3)C=C1OCCCN4CCCC4
Molecular Weight (g/mol) 329.44
Formula Weight 329.44
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
Show More Show Less

Research purposes only

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.