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6-Thioguanine, 98%
Description
6-Thioguanine acts as an antineoplastic and purine antimetabolite. It is also useful as an inhibition of stimulated expression of TNF-related apoptosis-inducing ligand (TRAIL) protein. It is involved in the treatment of acute leukemias and Psoriasis. Further, it is used for the treatment of ulcerative colitis and autoimmune diseases.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Soluble in dilute solutions of alkali hydroxides and hot alcohol. Insoluble in water.
Notes
Incompatible with strong oxidizing agents.
Specifications
Specifications
| Melting Point | >360°C |
| Assay Percent Range | 0.98 |
| Quantity | 1 g |
| UN Number | UN2811 |
| Beilstein | 157765 |
| Merck Index | 14,9337 |
| Solubility Information | Soluble in dilute solutions of alkali hydroxides and hot alcohol. Insoluble in water. |
| IUPAC Name | 2-amino-3,7-dihydropurine-6-thione |
| Formula Weight | 167.19 |
| Percent Purity | 98% |
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Safety and Handling
- 6-Thioguanine
- Danger
- Acute toxicity Category 3
- Germ cell mutagenicity Category 2
- H301-Toxic if swallowed.
- H341-Suspected of causing genetic defects.
- P264-Wash face, hands and anyexposed skin thoroughly after handling.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
- MIXTURE LIST-Contains : Thioguanine
RUO – Research Use Only
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