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SKF-86002, MedChemExpress

Product Code. 16457947
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Product Code. 16457947 Supplier Medchem Express Supplier No. HY12511

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Description

MedChemExpress SKF-86002 is an orally active p38 MAPK inhibitor, with anti-inflammatory, anti-arthritic and analgesic activities. SKF-86002 inhibits lipopolysaccharide (LPS)-stimulate human monocyte IL-1 and TNF-α production (IC50 = 1 μM). SKF-86002 inhibits lipoxygenase- and cyclooxygenase-mediated metabolism of arachidonic acid.

SKF-86002 is an orally active p38 MAPK inhibitor, with anti-inflammatory, anti-arthritic and analgesic activities. SKF-86002 inhibits lipopolysaccharide (LPS)-stimulate human monocyte IL-1 and TNF-α production (IC50 = 1 μM). SKF-86002 inhibits lipoxygenase- and cyclooxygenase-mediated metabolism of arachidonic acid.

Specifications

Chemical Name or Material SKF-86002
CAS 72873-74-6
Color Brown
Purity Grade Notes Research
Molecular Formula C16H12FN3S
Quantity 5 mg
Solubility Information DMSO : 33.33 mg/mL (112.09 mM; Need ultrasonic)
SMILES FC1=CC=C(C2=C(C3=CC=NC=C3)N4C(SCC4)=N2)C=C1
Molecular Weight (g/mol) 297.35
Formula Weight 297.35
Percent Purity 99.46%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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