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Fatostatin, MedChemExpress

Product Code. 16468677
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Product Code. 16468677

Brand: Medchem Express HY14452

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Description

MedChemExpress Fatostatin (125B11), a specific inhibitor of SREBP activation, impairs the activation of SREBP-1 and SREBP-2. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. Fatostatin decreases the transcription of lipogenic genes in cells. Fatostatin possesses antitumor properties, and lowers hyperglycemia in ob/ob mice.

Fatostatin (125B11), a specific inhibitor of SREBP activation, impairs the activation of SREBP-1 and SREBP-2. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. Fatostatin decreases the transcription of lipogenic genes in cells. Fatostatin possesses antitumor properties, and lowers hyperglycemia in ob/ob mice.

Specifications

Chemical Name or Material Fatostatin
CAS 125256-00-0
Color White
Purity Grade Notes Research
Molecular Formula C18H18N2S
Quantity 5 mg
Synonym 125B11
Solubility Information DMSO : ≥ 27 mg/mL (91.71 mM)
SMILES CCCC1=NC=CC(C2=NC(C3=CC=C(C)C=C3)=CS2)=C1
Molecular Weight (g/mol) 294.41
Formula Weight 294.41
Percent Purity 98.2%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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