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BAY-678, MedChemExpress

Product Code. 16430777
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Product Code. 16430777

Brand: Medchem Express HY111457A

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Description

MedChemExpress BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM. BAY-678 is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC).

BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM. BAY-678 is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC).

Specifications

Chemical Name or Material BAY-678
Physical Form Solid
CAS 675103-36-3
Color Yellow
Quantity 50 mg
Purity Grade Notes Research
Molecular Formula C20H15F3N4O2
For Use With (Application) COVID-19-immunoregulation
Solubility Information DMSO : ≥ 100 mg/mL (249.78 mM) ∣Ethanol : ≥ 4.76 mg/mL (11.89 mM)
SMILES N#CC1=NC=C([C@H](C(C(C)=O)=C(C)N2C3=CC=CC(C(F)(F)F)=C3)NC2=O)C=C1
Molecular Weight (g/mol) 400.35
Formula Weight 400.35
Percent Purity 99.24%
Grade Research
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Research purposes only

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