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4-Aminobutyric acid, 99+%

Product Code. 10775931 Shop All Thermo Scientific Chemicals Products
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Product Code. 10775931 Supplier Thermo Scientific Acros Supplier No. 103280250
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Description

4-Aminobutyric acid, 99+%, CAS # 56-12-2, also known as γ-Aminobutyric acid, is an amino acid that shows inhibitory activities against neurotransmitters, including GABA. | CAS: 56-12-2 | C4H9NO2 | 103.12 g/mol

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• 4-Aminobutyric acid is a γ-amino acid and monocarboxylic acid derived from butyric acid

• It is an amino acid that shows inhibitory activities against neurotransmitters, including GABA, and acts by binding GABA-A receptor and inhibiting the activity of signal-receiving neurons

• This compound, converted from neurotransmitter glutamate, is essential to regulate neuronal excitability

• It binds to GABA-A and GABA-B receptors, causing ion channel opening, hyperpolarization, and eventually inhibition of neurotransmission

Applications

• 4-Aminobutyric acid has been used in the preparation of GABA–BSA (bovine serum albumin)–GA (glutaraldehyde) conjugate, which is used as a control for immunohistochemical experiments

• It is used, in vivo, to detect GABA neurotransmitter by magnetic resonance spectroscopy

• This compound increases the production of short-chain fatty acids and decreases pH values in mouse colon

• Some in vivo experiments, using rats, mice, and pigs, demonstrated that 4-Aminobutyric acid can modulate intestinal fluid secretion, blood flow and ulceration

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 56-12-2
Molecular Formula C4H9NO2
Molecular Weight (g/mol) 103.12
MDL Number MFCD00008226
InChI Key BTCSSZJGUNDROE-UHFFFAOYSA-N
Synonym 4-aminobutyric acid, gaba, gamma-aminobutyric acid, piperidic acid, piperidinic acid, aminalon, gaballon, gammalon, mielogen, butanoic acid, 4-amino
PubChem CID 119
ChEBI CHEBI:16865
IUPAC Name 4-aminobutanoic acid
SMILES C(CC(=O)O)CN

Specifications

Melting Point 197°C to 204°C
CAS Min % 99.0
CAS Max % 100.0
Color White
Infrared Spectrum Authentic
Assay Percent Range 99+%
Loss on Drying 0.5% max.
Packaging Plastic Bottle
Linear Formula H2N(CH2)3CO2H
Beilstein 04,413
Merck Index 15,425
Transmittance 95% min. (c=10, 2N HCl, 430nm) 1cm cell
Solubility Information Solubility in water: very soluble. Other solubilities: slightly soluble in common solvents
Quantity 25 g
Formula Weight 103.12
Percent Purity ≥99%
Physical Form Crystalline Powder
Chemical Name or Material 4-Aminobutyric acid, 99+%
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