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  7. 4',5,7-Trihydroxyflavone, 97%, Thermo Scientific Chemicals

4',5,7-Trihydroxyflavone, 97%, Thermo Scientific Chemicals

Catalog Number 11368126
Click to view available options
Quantity:
25 mg
100 mg
520-36-5
C15H10O5
270.24
MFCD00006831
KZNIFHPLKGYRTM-UHFFFAOYSA-N
apigenin, 5,7-dihydroxy-2-4-hydroxyphenyl-4h-chromen-4-one, chamomile, spigenin, versulin, apigenol, 4',5,7-trihydroxyflavone, apigenine, c.i. natural yellow 1, 5,7,4'-trihydroxyflavone
5280443
CHEBI:18388
5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
OC1=CC=C(C=C1)C1=CC(=O)C2=C(O)C=C(O)C=C2O1
520-36-5
C15H10O5
270.24
MFCD00006831
KZNIFHPLKGYRTM-UHFFFAOYSA-N
apigenin, 5,7-dihydroxy-2-4-hydroxyphenyl-4h-chromen-4-one, chamomile, spigenin, versulin, apigenol, 4',5,7-trihydroxyflavone, apigenine, c.i. natural yellow 1, 5,7,4'-trihydroxyflavone
5280443
CHEBI:18388
5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
OC1=CC=C(C=C1)C1=CC(=O)C2=C(O)C=C(O)C=C2O1

Description

4',5,7-Trihydroxyflavone is a nonmutagenic flavonoid shown to inhibit cell proliferation, angiogenesis and protein kinase. Also induces apoptosis in breast cancer cells. It inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4′,5,7-Trihydroxyflavone is a nonmutagenic flavonoid shown to inhibit cell proliferation, angiogenesis and protein kinase. Also induces apoptosis in breast cancer cells. It inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication.

Solubility
Soluble in dimethyl sulfoxide (27 mg/ml) or 1M potassium hydroxide (50mg/ml).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with and strong oxidizing agents.
TRUSTED_SUSTAINABILITY
Melting Point ∽315°C (decomposition)
Quantity 100 mg
Beilstein 262620
Merck Index 14,730
Solubility Information Soluble in dimethyl sulfoxide (27mg/ml) or 1M potassium hydroxide (50mg/ml).
Formula Weight 270.24
Percent Purity 97%
Chemical Name or Material 4',5,7-Trihydroxyflavone

RUO – Research Use Only

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