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4',5,7-Trihydroxyflavone, 97%, Thermo Scientific Chemicals

Catalog Number 11358126
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Quantity:
25 mg
100 mg
This item is not returnable. View return policy
520-36-5
C15H10O5
270.24
MFCD00006831
KZNIFHPLKGYRTM-UHFFFAOYSA-N
apigenin, 5,7-dihydroxy-2-4-hydroxyphenyl-4h-chromen-4-one, chamomile, spigenin, versulin, apigenol, 4',5,7-trihydroxyflavone, apigenine, c.i. natural yellow 1, 5,7,4'-trihydroxyflavone
5280443
CHEBI:18388
5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
OC1=CC=C(C=C1)C1=CC(=O)C2=C(O)C=C(O)C=C2O1
This item is not returnable. View return policy
520-36-5
C15H10O5
270.24
MFCD00006831
KZNIFHPLKGYRTM-UHFFFAOYSA-N
apigenin, 5,7-dihydroxy-2-4-hydroxyphenyl-4h-chromen-4-one, chamomile, spigenin, versulin, apigenol, 4',5,7-trihydroxyflavone, apigenine, c.i. natural yellow 1, 5,7,4'-trihydroxyflavone
5280443
CHEBI:18388
5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
OC1=CC=C(C=C1)C1=CC(=O)C2=C(O)C=C(O)C=C2O1

4',5,7-Trihydroxyflavone is a nonmutagenic flavonoid shown to inhibit cell proliferation, angiogenesis and protein kinase. Also induces apoptosis in breast cancer cells. It inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4′,5,7-Trihydroxyflavone is a nonmutagenic flavonoid shown to inhibit cell proliferation, angiogenesis and protein kinase. Also induces apoptosis in breast cancer cells. It inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication.

Solubility
Soluble in dimethyl sulfoxide (27 mg/ml) or 1M potassium hydroxide (50mg/ml).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with and strong oxidizing agents.
TRUSTED_SUSTAINABILITY
Melting Point ∽315°C (decomposition)
Quantity 25 mg
Beilstein 262620
Merck Index 14,730
Solubility Information Soluble in dimethyl sulfoxide (27mg/ml) or 1M potassium hydroxide (50mg/ml).
Formula Weight 270.24
Percent Purity 97%
Chemical Name or Material 4',5,7-Trihydroxyflavone
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Product Identifier
  • 4',5,7-Trihydroxyflavone
Signal Word
  • Warning
Hazard Category
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
Hazard Statement
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.
  • P332+P313-If skin irritation occurs: Get medical advice/attention.
  • P337+P313-If eye irritation persists: Get medical advice/attention.
Supplemental information
  • MIXTURE LIST-Contains : 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-benzo pyrone

RUO – Research Use Only

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