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1A-116, MedChemExpress

Product Code. 16474966
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Product Code. 16474966 Supplier Medchem Express Supplier No. HY104064

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Description

MedChemExpress 1A-116, a potent Rac1 inhibitor, is specific for W56 residues, can prevent EGF-induced Rac1 activation and block Rac1-P-Rex1 interaction. 1A-116 can induce apoptosis and inhibit cell proliferation, migration and cycle progression in a concentration-dependent manner. 1A-116 also demonstrates a high antimetastatic activity in vivo.

1A-116, a potent Rac1 inhibitor, is specific for W56 residues, can prevent EGF-induced Rac1 activation and block Rac1-P-Rex1 interaction. 1A-116 can induce apoptosis and inhibit cell proliferation, migration and cycle progression in a concentration-dependent manner. 1A-116 also demonstrates a high antimetastatic activity in vivo.

Specifications

Chemical Name or Material 1A-116
Physical Form Solid
CAS 1430208-73-3
Color Off-White
Quantity 100 mg
Purity Grade Notes Research
Molecular Formula C16H16F3N3
For Use With (Application) Cancer-Kinase/protease
Solubility Information DMSO : 100 mg/mL (325.40 mM; Need ultrasonic)
SMILES N=C(NC1=CC=CC=C1C(F)(F)F)NC2=CC(C)=CC(C)=C2
Molecular Weight (g/mol) 307.31
Formula Weight 307.31
Percent Purity 99.39%
Grade Research
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