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14-3-3 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 2E10A3, Proteintech
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66061-1-Ig recognizes 14-3-3 tau (YWHAQ), eta (YWHAH), and zeta (YWHAZ), but not epsilon (YWHAE).
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5′ UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.
Specifications
Specifications
| Antigen | 14-3-3 |
| Applications | Immunohistochemistry (Paraffin), Immunocytochemistry, Western Blot, Flow Cytometry, Immunofluorescence |
| Classification | Monoclonal |
| Clone | 2E10A3 |
| Concentration | 0.71 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | YWHAQ |
| Gene Accession No. | P27348, P68254, P68255 |
| Gene Alias | 14 3 3, 14 3 3 protein T cell, 14 3 3 protein tau, 14 3 3 protein theta, 14-3-3 tau, HS1, Protein HS1, YWHAQ |
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