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OICR-9429, MedChemExpress
Description
OICR-9429 is high affinity WD repeat domain 5 (WDR5) inhibitor, competitively blocks WDR5 interaction with MLL protein via binding the central peptide-binding pocket of WDR5. OICR-9429 can suppress histone H3K4 trimethylation and can be used for the research of various cancers including non-MLL-rearranged leukaemia, colon, pancreatic, prostate cancer and bladder cancer (BCa) .
Specifications
Specifications
| Chemical Name or Material | OICR-9429 |
| Physical Form | Solid |
| CAS | 1801787-56-3 |
| Color | White |
| Quantity | 100 mg |
| Purity Grade Notes | Research |
| Molecular Formula | C29H32F3N5O3 |
| For Use With (Application) | Cancer-programmed cell death |
| Solubility Information | DMSO : ≥ 32 mg/mL (57.60 mM) |
| SMILES | O=C(C1=CNC(C=C1C(F)(F)F)=O)NC2=CC(C3=CC(CN4CCOCC4)=CC=C3)=CC=C2N5CCN(C)CC5 |
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Research purposes only
Product Title
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