The new Thermo Scientific™ Multidrop™ Pico 8 Surfactant-Free Digital Dispenser offers the precision and speed the original Multidrop Pico 8 was known for, without the need for surfactants when dispensing aqueous fluids. It offers enhanced dispensing precision with volumes as low as 8pL, using up to 10× less reagent than manual pipetting, reducing both costs and waste. Designed for assay miniaturization, it both boosts productivity and improves accuracy, ideal for qPCR, dose response curves, drug screening assays, and enzyme profiling. The intuitive Multidrop™ PicoIT software supports complex experimental setups, enhancing productivity and data integrity while conserving resources and improving operational efficiency.
Advanced Assay Miniaturization
Digital dispensing technology enables direct dilution and low dead volume, with precise fluid delivery in volumes as low as 8pL, enabling up to a 10-fold reduction in reagent and sample consumption.
Enhanced Workflow Efficiency and Sample Integrity
Non-contact disposable dispensing cartridges eliminate cross-contamination and carry-over. With a 40× increase in processing speed, typical dose experiments are completed in just 15 seconds, compared to 10 minutes with analog serial dilution. This minimizes manual pipetting steps and reduces the risk of repetitive strain injuries.
Intuitive Software
Multidrop™ PicoIT software provides flexible and intuitive experiment design capabilities for complex plate layouts. It supports sophisticated assay configurations while maintaining user-friendly operation through simplified setup procedures. Application-focused wizards and pre-programed protocol templates for qPCR master mixes provide automated fluid customization for each qPCR component. Complete traceability functionality tracks reagent amounts and dispensing times for each well after every run.
Wide Range of Applications
The Multidrop™ Pico 8 Surfactant-Free Digital Dispenser supports a variety of fluid types, including master mixes, DMSO-based fluids, and aqueous fluids, with or without small molecule components or biomolecules. Additionally, it can dispense aqueous fluids without surfactant using surfactant-free cartridges. As such it can automate complex protocols such as drug synergy/combination studies and multi-component titrations, and is ideal for applications including qPCR, DMPK, assay development, biochemical assays, secondary screening, cell-based assays, spotting, enzyme profiling, synthetic biology, antibody therapies, and SAR.
Instrument Options and Capabilities
The Pico 8 Dispenser is specifically designed for complex multi-reagent/sample assays in high-density formats (up to 1536-well plates), using 4-channel or 8-channel standard or surfactant-free cartridges. For labs looking to drive efficiency and savings in their assay miniturization workflow, this new Thermo Scientific™ product is a must have.
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Catalog Number 31337546