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Geltrex Flex Basement Membrane Matrices

New formats, new applications​.

Geltrex Flex Basement Membrane Matrices

Why Choose Gibco™ Geltrex™ Flex?

Save Money

Avoid paying high upfront costs for volume you don’t need.

Save money

Minimize Variability

Freeze-thaw cycles of stored surplus can be less of a concern.

Minimize variability

Reduce Contamination Risks

No need to aliquot extra volume.

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Applicable Solutions

BINDER Cooling Incubators and Constant Climate Chambers

What is Geltrex Flex Matrix?

Geltrex Flex matrix is a basement membrane extract that contains laminin, collagen IV, entactin, and heparan sulfate proteoglycans It supports growth of a variety of cells in 2D and 3D cell culture, including primary cells, human pluripotent stem cells and the culture of organoids & tumoroids.​

Geltrex Flex Example Data and Products by Application

The right matrix supports cell structure, influences functions, and recreates an in vivo environment for more physiological relevance.  Explore the data comparing Geltrex Flex, Geltrex and competitor matrix by your research area. 

1. General Cell Culture

Geltrex™ Flex LDEV-Free Reduced Growth Factor Basement Membrane Matrix is designed to provide a substrate for cell attachment, growth, and differentiation, mimicking the extracellular matrix. Explore the representative data comparing Geltrex™ Flex, Competitor M, and Geltrex in hepatocyte culture and tube formation assays for angiogenesis.

2. Stem Cell Culture

A qualified stem cell matrix ensures cell viability, supports proper differentiation, and maintains pluripotency, providing a consistent and optimal environment for reliable and reproducible research outcomes. Our Geltrex™ Flex LDEV-Free hESC Qualified Reduced Growth Factor Basement Membrane Matrix is validated to promote hESC and hiPSC stem cell attachment and effectively maintain iPSC in a pluripotent state.

3. Organoid Cell Culture

An organoid-qualified matrix helps in the culture of organoids as it supports their 3D structure, promotes cell viability and growth, facilitates functional differentiation, and helps ensure experimental reproducibility. Geltrex Flex LDEV-Free Organoid-Qualified Reduced Growth Factor Basement Membrane Matrix supports culture of mouse intestinal, liver ductal, and airway organoids as well as expansion of mouse small intestinal. Geltrex Flex matrix also supports growth of colorectal cancer organoids (tumoroids) in stable 3D dome structures as well as in suspension.​

FAQ

The composition of Geltrex Flex is a proprietary formulation of laminin, collagen IV, entactin, and heparan sulfate proteoglycans . The composition of Geltrex is also proprietary and has similar key proteins in its formula.

The recommended version of Geltrex Flex is listed in the table below depending on the type of Geltrex you utilized. Geltrex Flex is also offered in 10mL sizes as well as in an organoid qualified versionpreviously not available. Data comparing Geltrex to Geltrex Flex can be explored here.

All our matrix products are phenol red-free to help ensure precise color detection and eliminate estrogenic effects in your research. Phenol red can be added for customized needs, helping provide you with versatile and reliable cell culture solutions.​