missing translation for 'onlineSavingsMsg'
Learn More

Vimentin Mouse anti-Canine, Chicken, Human, Rat, Clone: V9, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-9897-80

Additional Details : Weight : 0.01000kg

 View more versions of this product

Product Code. 15268217

  • 822.00 NOK / 25µg


In Stock 4
Add to basket

Description

Description

Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin. It is believed to be involved with the intracellular transport of proteins between the nucleus and plasma membrane. Unlike other IFP proteins, vimentin is expressed, along with desmin, during the early stages of cellular development. During the development process, vimentin is exchanged for new, tissue-specific IFPs. Vimentin has been implicated to be involved in the rate of steroid synthesis via its role as a storage network for steroidogenic cholesterol containing lipid droplets. Vimentin phosphorylation by a protein kinase causes the breakdown of intermediate filaments and activation of an ATP and myosin light chain dependent contractile event. This results in cytoskeletal changes that facilitate the interaction of the lipid droplets within mitochondria, and subsequent transport of cholesterol to the organelles leading to an increase in steroid synthesis.
Specifications

Specifications

Vimentin
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P09654, P31000, P08670
VIM, FLJ36605
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Canine, Chicken, Human, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
V9
Unconjugated
VIM
Liquid
VIM
IgG1, kappa
25 μg
4° C
Primary
420519, 477991, 7431, 81818
Videos

For Research Use Only.