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Invitrogen™ Human ULK1, GST Tag Recombinant Protein
ULK1 is a serine/threonine protein kinase that plays critical role during initial stages of autophagy which is a vital response to nutrient starvation. Recombinant human ULK1 (1-649) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
3765.00 NOK - 58300.00 NOK
Specifications
Gene Alias | ATG1, UNC51, Unc51.1, FLJ38455 |
---|---|
Protein Length | aa 1-649 |
Species | Human |
Recombinant | Recombinant |
Protein Tag | GST Tag |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15431234
|
Invitrogen™
PV6430 |
10μg |
3765.00 NOK
10µg |
Estimated Shipment: 07-05-2024 Log in to see stock. |
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15409053
|
Invitrogen™
PV6431 |
100μg |
13020.00 NOK
100µg |
Estimated Shipment: 07-05-2024 Log in to see stock. |
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15419053
|
Invitrogen™
PV6432 |
1mg |
58300.00 NOK
1mg |
Estimated Shipment: 07-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
The conserved C-terminal domain (CTD) of ULK1 controls the regulatory function and localization of the protein. Knockdown of ULK1 inhibits the autophagic response as well as inhibiting rapamycin-induced autophagy consistent with a role downstream of mTOR. ULK1 forms a complex with FIP200 and ATG13 and this complex is essential for starvation-induced autophagy. Both FIP200 and ATG13 are critical for correct localization of ULK1 to the pre-autophagosome and stability of ULK1 protein. ULK1 is phosphorylated by the mTOR pathway in a nutrient starvation-regulated manner.
- Validated in LanthaScreen™ Kinase Binding Assay
- Protocols available for simple use and optimized performance
- Multiple pack sizes available for convenient use
Specifications
ATG1, UNC51, Unc51.1, FLJ38455 | |
Human | |
GST Tag |
aa 1-649 | |
Recombinant |