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Invitrogen™ Human GPX4, Recombinant Protein

Recombinant Protein

Brand:  Invitrogen™ LFP0015

Additional Details : Weight : 0.99000kg

Product Code. 10765281

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Description

Description

Glutathione Peroxidase 4 (Hu) Recombinant Protein, LF-P0015, from Invitrogen.

Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione. There are several isoforms which differ in their primary structure and localization. The classical cytosolic/ mitochondrial GPx1 (cGPx) is a selenium-dependent enzyme, first of the GPx family to be discovered. GPx2, also known as gastrointestinal GPx (GI-GPx), is an intracellular enzyme expressed only at the epithelium of the gastrointestinal tract. Extracellular plasma GPx (pGPx or GPx3) is mainly expressed by the kidney from where it is released into the blood circulation. Phospholipid hydroperoxide GPx4 (PH-GPx) expressed in most tissues, can reduce many hydroperoxides including hydroperoxides integrated in membranes, hydroperoxy lipids in low density lipoprotein or thymine. All mammalian GPx family members, except for the recently described Cys containing GPx3 and epididymis-specific secretory GPx (eGPx or GPx5) isoforms, possess selenocysteine at the active site. This protein corresponds to human Glutathione Peroxidase 4 (25-197 aa Cysteine is substituted for Sec73), which has a molecular weight of 19 kDa. Purity: >95% by SDS-PAGE. After reconstitution, store at -80°C and avoid freeze and thaw cycles.
Specifications

Specifications

P36969
0.02M sodium phosphate with 0.05M NaCl and no preservative; pH 6.0
Human GPX4
500μg
-20°C, Avoid Freeze/Thaw Cycles
Human GPX4
Human
Hu
Recombinant
Recombinant
Control
2879
6.0
E. coli
RUO
GPX4
Unconjugated
E. coli
Lyophilized
purified
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