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RNF144B/IBRDC2 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 26306-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16884815

  • 1281.92 NOK / 20µL
Estimated Shipment: 19-12-2022
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Description

Description

E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se.
Specifications

Specifications

RNF144B/IBRDC2
Polyclonal
Unconjugated
RNF144B
IBRDC2, KIAA0161, p53RFP, ring finger protein 144B, RNF144B
Rabbit
Antigen Affinity Chromatography
RUO
255488
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin), Immunoprecipitation
0.3 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q7Z419
RNF144B
RNF144B/IBRDC2 Fusion Protein Ag23679
20 μL
Primary
Human
Antibody
IgG
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