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PPM1F Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 17020-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16886824

  • 3468.15 NOK / 150µL
Estimated Shipment: 20-12-2022
to see stock.

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Description

Description

PPM1F is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis.
Specifications

Specifications

PPM1F
Polyclonal
Unconjugated
PPM1F
CaM kinase phosphatase, CaMKPase, FEM 2, hFEM 2, KIAA0015, Partner of PIX 2, POPX2, PPM1F, Protein fem 2 homolog, Protein phosphatase 1F
Rabbit
Antigen Affinity Chromatography
RUO
287931, 68606, 9647
-20°C
Liquid
Western Blot, Immunoprecipitation, Immunofluorescence, Immunocytochemistry
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P49593, Q8CGA0, Q9WVR7
Ppm1f
PPM1F Fusion Protein Ag10186
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
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