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Nur77 Mouse anti-Mouse, Alexa Fluor® 488, Clone: 12.14, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 53-5965-80

Additional Details : Weight : 0.09500kg

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Product Code. 15590227

  • 1098.00 NOK / 25µg


Estimated Shipment
20-08-2020
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Description

Description

Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser. Filtration: 0.2 μm post-manufacturing filtered. NR4A1 is a member of the steroid-thyroid hormone-retinoid receptor superfamily. NGFI-B-alpha is expressed in brain, adrenal, thyroid, liver, testis, ovary, thymus, muscle, lung and prostate. Its expression is induced in response to various stress stimuli and growth factors. The encoded protein acts as a nuclear transcription factor involved in mediating apoptotic signaling in thymocytes and tumor cells, as well as having a role in signaling in the hypothalamic-pituitary axis. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Three transcript variants encoding two distinct isoforms have been identified for this NR4A1. Variant (3), also known as TRC beta, contains multiple differences compared to variant 1. The resulting isoform b contains a shorter and distinct C-terminus compared to isoform a. RXR has been shown to be a partner for NR4A1.
Specifications

Specifications

Nur77
Monoclonal
0.5 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P12813
early response protein NAK1; GFRP1; growth factor-inducible nuclear protein N10; HMR; hormone receptor; N10; NAK-1; nerve growth factor IB nuclear receptor variant 1; NGFIB; NP10; nuclear hormone receptor NUR/77; nuclear protein N10; nuclear receptor subfamily 4 group A member 1; nuclear receptor subfamily 4, group A, member 1; orphan nucle; orphan nuclear receptor HMR; orphan nuclear receptor TR3; ST-59; steroid receptor TR3; testicular receptor 3; TR3; TR3 orphan receptor
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
12.14
Alexa Fluor™ 488
Nr4a1
Liquid
Nr4a1
IgG1, kappa
25 μg
4° C, store in dark, DO NOT FREEZE!
Primary
15370
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For Research Use Only.