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N-Boc-D-phenylglycine, 99%, Thermo Scientific Chemicals

Catalog Number p-7047288
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Quantity:
1 g
5 g
This item is not returnable. View return policy
33125-05-2
C13H17NO4
251.28
MFCD00062043,MFCD00065588
HOBFSNNENNQQIU-UHFFFAOYNA-N
boc-d-phg-oh, boc-d-phenylglycine, n-boc-d-phenylglycine, n-boc-d-2-phenylglycine, n-boc-l-phenylglycine, n-tert-butoxycarbonyl-d-2-phenylglycine, boc-d-alpha-phenylglycine, r-tert-butoxycarbonyl amino phenyl acetic acid, r-tert-butoxycarbonylamino-phenyl-acetic acid, r-2-tert-butoxycarbonyl amino-2-phenylacetic acid
2755953
(2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-2-phenylacetic acid
CC(C)(C)OC(=O)NC(C(O)=O)C1=CC=CC=C1
This item is not returnable. View return policy
33125-05-2
C13H17NO4
251.28
MFCD00062043,MFCD00065588
HOBFSNNENNQQIU-UHFFFAOYNA-N
boc-d-phg-oh, boc-d-phenylglycine, n-boc-d-phenylglycine, n-boc-d-2-phenylglycine, n-boc-l-phenylglycine, n-tert-butoxycarbonyl-d-2-phenylglycine, boc-d-alpha-phenylglycine, r-tert-butoxycarbonyl amino phenyl acetic acid, r-tert-butoxycarbonylamino-phenyl-acetic acid, r-2-tert-butoxycarbonyl amino-2-phenylacetic acid
2755953
(2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-2-phenylacetic acid
CC(C)(C)OC(=O)NC(C(O)=O)C1=CC=CC=C1

It is a reagent of choice for assignment of absolute configuration of chiral primary amines by 1H NMR, giving better results than Mosher's acid ((R)-(+)-Methoxy-(trifluoromethyl)­phenyl­acetic acid. αR)-α-[[(1,1-Dimethylethoxy)carbonyl]amino]-benzeneacetic Acid is D-(+)-2-Phenylglycine with Boc protecting group. (αR)-α-[[(1,1-Dimethylethoxy)carbonyl]amino]-benzeneacetic Acid is used as part of a catalyst combination to catalyze regioselective [4 + 2] cycloadditions of β-substituted cyclic enones and polyconjugated malononitriles. It can also be used to catalyze stereoselective preparation of polyfunctional nitrocyclohexene carboxaldehydes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is a reagent of choice for assignment of absolute configuration of chiral primary amines by 1H NMR, giving better results than Mosher′s acid ((R)-(+)-ɑ-Methoxy-ɑ-(trifluoromethyl)­phenyl­acetic acid. αR)-α-[[(1,1-Dimethylethoxy)carbonyl]amino]-benzeneacetic Acid is D-(+)-2-Phenylglycine with Boc protecting group. (αR)-α-[[(1,1-Dimethylethoxy)carbonyl]amino]-benzeneacetic Acid is used as part of a catalyst combination to catalyze regioselective [4 + 2] cycloadditions of β-substituted cyclic enones and polyconjugated malononitriles. It can also be used to catalyze stereoselective preparation of polyfunctional nitrocyclohexene carboxaldehydes.

Solubility
Insoluble in water. Slightly soluble in DMSO and methanol.

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
TRUSTED_SUSTAINABILITY
Melting Point 90°C to 92°C
Beilstein 3033982
Solubility Information Insoluble in water. Slightly soluble in DMSO and methanol.
Formula Weight 251.28
Percent Purity 99%
Quantity 1 g
Optical Rotation −144° (c=1 in Ethanol)
Chemical Name or Material N-Boc-D-phenylglycine

RUO – Research Use Only

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