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ACROBiosystems Mouse Siglec-15 / CD33L3 Protein, His Tag

Brand:  ACROBiosystems SG5-M52H7-1mg

Additional Details : Weight : 0.00010kg

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Product Code. 16448039

  • 32169.11 NOK / 1mg
Estimated Shipment: 16-01-2023
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Description

Description

Siglec-15 is a DAP12-associated immunoreceptor, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. Siglecs are cell surface proteins that bind sialic acid. They are found primarily on the surface of immune cells and are a subset of the I-type lectins. Siglec-15 consisting of immunoglobulin (Ig)-like domains, transmembrane domain and a short cytoplasmic tail. Siglec-15 is that recognizes sialylated glycans and regulates osteoclast differentiation. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 27.5 kDa. The protein migrates as 33-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifications

Specifications

NP_001094508.1
27.5 kDa
1 mg
Arg 24 - Thr 262
CD33 antigen-like 3,SIGLEC-15,CD33L3,sialic acid-binding Ig-like lectin 15,Siglec15,Siglec-15
Unconjugated
PBS with Arginine, pH7.4
HEK293
Mouse
Powder
>90% as determined by SDS-PAGE
Mouse Siglec-15, His Tag (SG5-M52H7) is expressed from human 293 cells (HEK293). It contains AA Arg 24 - Thr 262 (Accession # A7E1W8-1).
-20°C
Siglec-15
His Tag
Less than 1.0 EU / µg by the LAL method.
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