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LAP (Latency Associated peptide) Monoclonal Antibody (TW7-16B4), PerCP-eFluor™ 710, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 46-9821-82

2160.10 NOK valid until 2024-03-29
Use promo code "21615" to get your promotional price.



Additional Details : Weight : 0.25000kg

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Product Code. 15371400

  • 3240.00 NOK / 100µg
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Description

Description

Description: The TW7-16B4 monoclonal antibody reacts with mouse latency associated peptide (LAP, pro-TGF beta 1, LAP/TGF beta 1). Many different cells produce TGF beta and it mediates effects on the proliferation, differentiation and function of many cell types. TGF beta is synthesized as a precursor that contains LAP at the N-terminus and mature TGF beta at the C-terminus. Processing and cleavage of the precursor protein between amino acids 278 and 279 results in the formation of LAP dimers and TGF beta dimers that then non-covalently associate with each other to form the small latent TGF beta complex. LAP is secreted and can be found in the extracellular matrix. In addition, LAP can also be expressed on platelets and activated regulatory T cells. It is believed that this surface-expressed LAP is due to the binding of LAP to GARP (LRRC32), which is a transmembrane protein that is also found at high levels on platelets and activated regulatory T cells. Applications Reported: This TW7-16B4 antibody has been reported for use in flow cytometric analysis. Applications Tested: This TW7-16B4 antibody has been tested by flow cytometric analysis of stimulated mouse splenocytes. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.

LAP (Latency Associated peptide) Monoclonal antibody specifically detects LAP (Latency Associated peptide) in Mouse samples. It is validated for Flow Cytometry.
Specifications

Specifications

LAP (Latency Associated peptide)
Monoclonal
0.2 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P04202
TGFB1
Affinity chromatography
RUO
21803
4° C, store in dark, DO NOT FREEZE!
Liquid
Flow Cytometry
TW7-16B4
PerCP-eFluor 710
TGFB1
CED; DPD1; LAP; latency-associated peptide; prepro-transforming growth factor beta-1; regulatory protein; TGFB; Tgfb1; Tgfb-1; TGFbeta; TGF-beta 1; TGFbeta1; TGF-beta1; TGF-beta-1; transforming growth factor beta 1; transforming growth factor beta-1; Transforming growth factor beta-1 proprotein; transforming growth factor, beta 1; transforming growth factor-beta 1
Mouse
100 μg
Primary
Mouse
Antibody
IgG1 κ
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