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KI67 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 27309-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16885555

  • 1281.92 NOK / 20µL
Estimated Shipment: 14-12-2022
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Description

Description

Ki-67 is a nuclear protein that is expressed during various stages in the cell cycle, particularly during late G1, S, G2, and M phases. The protein has a forkhead associated domain (FHA) through which it associates with euchromatin at the perichromosomal layer, the centromeric heterochromatin, and the nucleolus. Ki-67 is shown to have a cell cycle dependent topographical distribution with perinucleolar expression at G1, expression in the nuclear matrix at G2, and expression on the chromosomes during M phase. Ki-67 is commonly used as a proliferation marker because it is not detected in G0 cells, but increases steadily from G1 through mitosis. Ki-67 antibodies are useful in establishing the cell growing fraction in neoplasms. In neoplastic tissues, the prognostic value is comparable to the tritiated thymidine-labelling index. The correlation between low Ki-67 index and histologically low-grade tumors is strong. Ki-67 is routinely used as a neuronal marker of cell cycling and proliferation.
Specifications

Specifications

KI67
Polyclonal
Unconjugated
MKI67
Antigen KI 67, Ki 67, KI67, KIA, MKI67
Rabbit
Antigen Affinity Chromatography
RUO
4288
-20°C
Liquid
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
0.6 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P46013
MKI67
KI67 Fusion Protein Ag26266
20 μL
Primary
Human
Antibody
IgG
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