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IRF4 Rat anti-Human, Mouse, Clone: 3E4, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-9858-80

Additional Details : Weight : 0.01000kg

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Product Code. 15208197

  • 850.00 NOK / 25µg


Estimated Shipment
18-08-2020
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Description

Description

Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered. The IRF (interferon regulatory factor) family of transcription factors are characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. IRF4 is lymphocyte specific and negatively regulates toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found.
Specifications

Specifications

IRF4
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
Q15306, Q64287
LSIRF, MUM1
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Human, Mouse
Western Blot
3E4
Unconjugated
IRF4
Liquid
IRF4
IgG1, kappa
25 μg
4° C
Primary
16364, 3662
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