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Integrin beta 7 Rat anti-Human, Mouse, PE-Cyanine7, Clone: FIB504, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 25-5867-41

Additional Details : Weight : 0.23750kg

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Product Code. 15588576

  • 1008.00 NOK / 25 tests


Estimated Shipment
14-09-2020
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Description

Description

Please protect this vial and stained samples from light. Fixation: Samples can be stored in IC Fixation Buffer (cat. 00-8222) (100 µL of cell sample + 100 µL of IC Fixation Buffer) or 1-step Fix/Lyse Solution (cat. 00-5333) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation. Some generalizations regarding fluorophore performance after fixation can be made, but clone specific performance should be determined empirically. Excitation: 488-561 nm; Emission: 775 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered. Integrin beta 7 associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Ligands for LPAM-1 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the ligand of HML-1 is E-cadherin (CD324). Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response.
Specifications

Specifications

Integrin Beta 7
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P26010, P26011
Integrin beta-7, Gut homing receptor beta subunit, ITGB7
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Human, Mouse
Flow Cytometry
FIB504
PE-Cyanine7
ITGB7
Liquid
ITGB7
IgG2a, kappa
25 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
16421, 3695
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For Research Use Only.