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Integrin beta-3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 18309-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16888384

  • 3468.15 NOK / 150µL
Estimated Shipment: 16-12-2022
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Description

Description

ITGB3 is involved in Glanzmann thrombasthenia (GT), a common inherited disease of platelet aggregation. It is characterized by mucocutaneous bleeding of mild-to-moderate severity. GT has been classified clinically into types I and II. In type I, platelets show absence of the glycoprotein IIb-IIIa complexes at their surface and lack fibrinogen and clot retraction capability. In type II, the platelets express the GPIIb-IIIa complex at reduced levels, have detectable amounts of fibrinogen, and have low or moderate clot retraction capability. The disease is caused by mutations affecting the gene represented in this entry.
Specifications

Specifications

Integrin beta-3
Polyclonal
Unconjugated
ITGB3
CD61, GP3A, GPIIIa, Integrin beta 3, Integrin beta-3, ITGB3
Rabbit
Antigen Affinity Chromatography
RUO
16416, 29302, 3690
-20°C
Liquid
Western Blot, Immunoprecipitation
0.27 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O54890, P05106
ITGB3
Peptide
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
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