IL-4 Mouse anti-Rat, eFluor® 660, Clone: OX81, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 50-7045-80
Additional Details : Weight : 0.25000kg
DescriptionExcitation: 633-647 nm; Emission: 668 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered. Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|Interleukin-4, BSF1, IL-4, Lymphocyte stimulatory factor 1, MGC79402|
|4° C, store in dark, DO NOT FREEZE!|
For Research Use Only.