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IL-31 Monoclonal Antibody (31SNEZE), eFluor™ 660, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

1162.00 NOK - 3340.00 NOK

Specifications

Antigen IL-31
Clone 31SNEZE
Concentration 5 μL/Test
Applications Flow Cytometry
Classification Monoclonal
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Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15500097
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Affymetrix eBioscience
50-9319-42
100 Tests
3340.00 NOK
100 tests
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Estimated Shipment: 10-04-2024
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15590087
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Affymetrix eBioscience
50-9319-41
25 Tests This item is currently unavailable or has been discontinued.
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Descripción

Descripción

Description: This 31SNEZE monoclonal antibody reacts with human IL-31. Interleukin-31 (IL-31) is a recently-discovered member of the IL-6 family of cytokines. It is expressed by CD4+ T cells, particularly those with a Th2 phenotype, and mast cells. The IL-31 receptor is a heterodimer composed of one IL-31RA and one OSMR beta subunit. This receptor is constitutively expressed by various cells types, including macrophages, monocytes, eosinophils, keratinocytes, and epithelial cells. IL-31 receptor signaling leads to STAT3 activation and promotes the release of proinflammatory cytokines and chemokines, such as IL-1 beta, IL-6, IL-8, CXCL1, and CCL2. Over-expression of IL-31 is observed in patients with allergic asthma, allergic rhinitis, and atopic dermatitis, with a positive correlation between circulating levels and disease severity. Applications Reported: This 31SNEZE antibody has been reported for use in intracellular staining followed by flow cytometric analysis. Applications Tested: This 31SNEZE antibody has been pre-titrated and tested by intracellular staining followed by flow cytometric analysis of human peripheral blood lymphocytes. This can be used at 5 μL (0.125 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.

IL-31 Monoclonal antibody specifically detects IL-31 in Human samples. It is validated for Flow Cytometry.
Especificaciones

Especificaciones

IL-31
5 μL/Test
Monoclonal
Liquid
RUO
Q6EBC2
IgG2b κ
Affinity chromatography
Antibody
31SNEZE
Flow Cytometry
eFluor 660
Mouse
Human
386653
Primary
4° C, store in dark, DO NOT FREEZE!
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For Research Use Only.