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Proteintech HumanKine™ recombinant human IL-12 beta protein
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10 μg
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Description
IL-12p40, also known as IL-12B, is a subunit of both the IL-12 and IL-23 cytokines. It is not thought to be bioactive on its own, but it has been shown to regulate IL-12 activity in antagonistic manner by competitively binding with the IL-12 receptor. IL-12p40 also functions as a chemoattractant molecule for macrophage infiltration into tumor sites. There has additionally been evidence to suggest that IL-12p40 mediates a protective immune response against mycobacterial infection by serving as a necessary component for granuloma formation and promoting Th1 effector cell functions (PMID: 17126601, 10453037, 11739515).
Spécification
Spécification
| Accession Number | P29460 |
| Formulation | 1 x PBS pH 7.4 |
| Gene ID (Entrez) | 3593 |
| Molecular Weight (g/mol) | 37-50 kDa |
| Quantity | 10 μg |
| Source | HEK293 |
| Storage Requirements | Lyophilized product should be stored at -20°C to -80°C until expiry date and (at Room Temperature for 2 weeks.) |
| Endotoxin Concentration | <0.1 EU/μg |
| Specific Reactivity | Human |
| Recombinant | Recombinant |
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