missing translation for 'onlineSavingsMsg'
Learn More
Learn More
ACROBiosystems Human TRAIL / TNFRSF10 Protein, Mouse IgG2a Fc Tag
5341.70 NOK - 39223.36 NOK
Specifications
| Accession Number | NP_003801.1 |
|---|---|
| Molecular Weight (g/mol) | 46.4 kDa |
| Source | Human TRAIL, Mouse IgG2a Fc Tag (TRL-H5259) is expressed from human 293 cells (HEK293). It contains AA Val 114 - Gly 281 (Accession # P50591-1). |
| Immunogen | Val 114 - Gly 281 |
| Storage Requirements | -20°C |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
16448129
|
ACROBiosystems
TRL-H5259-1MG |
1 mg |
39223.36 NOK
1mg |
Estimated Shipment: 30-04-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
|
16438129
|
ACROBiosystems
TRL-H5259-100UG |
100 μg |
5341.70 NOK
100µg |
Estimated Shipment: 30-04-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
TRAIL, also known as TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL, TNLG6A and TNF superfamily member 10. The TRAIL gene as a drug target, induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis. TRAIL also binds the receptors DcR1 and DcR2, which do not contain a cytoplasmic domain (DcR1) or contain a truncated death domain (DcR2). DcR1 functions as a TRAIL-neutralizing decoy-receptor. The cytoplasmic domain of DcR2 is functional and activates NFkappaB. In cells expressing DcR2, TRAIL binding therefore activates NFkappaB, leading to transcription of genes known to antagonize the death signaling pathway and/or to promote inflammation.
This protein carries a mouse IgG2a Fc tag at the N-terminus. The protein has a calculated MW of 46.4 kDa. The protein migrates as 47-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Specifications
| NP_003801.1 | |
| Human TRAIL, Mouse IgG2a Fc Tag (TRL-H5259) is expressed from human 293 cells (HEK293). It contains AA Val 114 - Gly 281 (Accession # P50591-1). | |
| -20°C | |
| TRAIL | |
| Human | |
| Tris with Glycine, Arginine and NaCl, pH7.5 | |
| HEK293 | |
| Cytokines and Growth Factors |
| 46.4 kDa | |
| Val 114 - Gly 281 | |
| Apo-2 L,TRAIL,CD253,TNFSF10,Apo-2 ligand | |
| Unconjugated | |
| Mouse IgG Fc Tag | |
| Less than 0.1 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |