Invitrogen™ Osteopontin Human ELISA Kit
For the quantitative detection of human Osteopontin.
Brand: Invitrogen™ BMS2066
Additional Details : Weight : 0.23750kg
DescriptionOsteopontin is an arginine-glycine-aspartic acid (RGD)-containing glycoprotein that interacts with integrins and CD44 as major receptors. It is a multifunctional protein involved in bone mineralization, cell adhesion, cell migration, chronic inflammatory disease and transformation. Proteolytic cleavage by thrombin and matrix metalloproteinases close to the integrin-binding Arg-Gly-Asp sequence modulates the function of OPN and its integrin binding properties. Thrombin-cleaved fragments of Osteopontin are overexpressed in malignant glial tumors and provide a molecular niche with survival advantage and provide a novel substrate for plasmin and cathepsin D.
|Plasma, 20 μL|Serum, 20 μL|Supernatant, 20 μL|
|1 hr. 20 min.|
|OPN, ETA-1, BSP-1, SPP1|
|Pre-coated 96 well plate, Standard, Sample Diluent, Assay Buffer concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers|
|2°C to 8°C|
|4 hr. 30 min.|
|Colorimetric Microplate Reader|
For Research Use Only