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Abnova™ Human NPC1 Partial ORF (AAH63302, 151 a.a. - 250 a.a.) Recombinant Protein with GST-tag at N-terminal

Used for AP, Array, ELISA, WB-Re

4115.00 NOK - 6245.00 NOK

Specifications

Accession Number AAH63302
For Use With (Application) Antibody Production, ELISA, Protein Array, Western Blot
Formulation 50mM Tris-HCI, 10mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene ID (Entrez) 4864
Molecular Weight (g/mol) 36.63kDa
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16188451
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Abnova™
H00004864-Q01.10UG
10 ug
4115.00 NOK
10µg
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Estimated Shipment: 27-05-2024
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16198451
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Abnova™
H00004864-Q01.25UG
25 ug
6245.00 NOK
25µg
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Estimated Shipment: 27-05-2024
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Description

Description

This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments

Sequence: GFANAMYNACRDVEAPSSNDKALGLLCGKDADACNATNWIEYMFNKDNGQAPFTITPVFSDFPVHGMEPMNNATKGCDESVDEVTAPCSCQDCSIVCGPK
Specifications

Specifications

AAH63302
50mM Tris-HCI, 10mM reduced Glutathione, pH=8.0 in the elution buffer.
36.63kDa
12.5% SDS-PAGE Stained with Coomassie Blue.
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
NPC
NPC1
Recombinant
wheat germ expression system
Antibody Production, ELISA, Protein Array, Western Blot
4864
NPC1 (Human) Recombinant Protein (Q01)
GFANAMYNACRDVEAPSSNDKALGLLCGKDADACNATNWIEYMFNKDNGQAPFTITPVFSDFPVHGMEPMNNATKGCDESVDEVTAPCSCQDCSIVCGPK
RUO
NPC1
Wheat Germ (in vitro)
GST
Liquid
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SDS
Documents

Documents

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