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Abnova™ Human MAP3K7IP1 Partial ORF (NP_705717.1, 3 a.a. - 100 a.a.) Recombinant Protein with GST-tag at N-terminal

Used for AP, Array, ELISA, WB-Re

4115.00 NOK - 6245.00 NOK

Specifications

Accession Number NP_705717.1
For Use With (Application) Antibody Production, ELISA, Protein Array, Western Blot
Formulation 50mM Tris-HCI, 10mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene ID (Entrez) 10454
Molecular Weight (g/mol) 36.52kDa
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Product Code Brand Quantity Price Quantity & Availability  
16152546
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Abnova™
H00010454-Q01.25UG
25 ug
6245.00 NOK
25µg
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Estimated Shipment: 14-06-2024
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16142546
View Documents Promotion Details
Abnova™
H00010454-Q01.10UG
10 ug
4115.00 NOK
10µg
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»
Estimated Shipment: 14-06-2024
to see stock.
Please to purchase this item. Need a web account? Register with us today!
Description

Description

The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]

Sequence: AQRRSLLQSEQQPSWTDDLPLCHLSGVGSASNRSYSADGKGTESHPPEDSWLKFRSENNCFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLNAEHAEA
Specifications

Specifications

NP_705717.1
50mM Tris-HCI, 10mM reduced Glutathione, pH=8.0 in the elution buffer.
36.52kDa
12.5% SDS-PAGE Stained with Coomassie Blue.
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
3'-Tab1/MGC57664/TAB1
MAP3K7IP1
Recombinant
wheat germ expression system
Antibody Production, ELISA, Protein Array, Western Blot
10454
MAP3K7IP1 (Human) Recombinant Protein (Q01)
AQRRSLLQSEQQPSWTDDLPLCHLSGVGSASNRSYSADGKGTESHPPEDSWLKFRSENNCFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLNAEHAEA
RUO
MAP3K7IP1
Wheat Germ (in vitro)
GST
Liquid
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SDS
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Documents

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