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ACROBiosystems Human IL-17A / CTLA-8 Protein, Tag Free
MALS verified
POA
Specifications
Molecular Weight (g/mol) | 15.3 kDa |
---|---|
Source | Human IL17A, Tag Free (ILA-H5118) is expressed from E.coli cells. It contains AA Gly 24 - Ala 155 (Accession # Q16552). |
Immunogen | Gly 24 - Ala 155 |
Storage Requirements | -20°C |
Gene Alias | IL-17 A,Interleukin-17 A,CTLA-8,IL-17 |
Description
Interleukin-17A (IL17A) is also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA8),which is a proinflammatory cytokine produced by activated T cells. IL17A can regulate the activities of NF-kappaB and mitogen-activated protein kinases. Also,IL17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).Furthermore,IL17A has been found both in glycosylated and nonglycosylated forms. High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
This protein carries no "e;tag"e;. The protein has a calculated MW of 15.3 kDa. the protein migrates as 18 kDa under reducing (R) condition, and 28 kDa under non-reducing (NR) condition (SDS-PAGE).Specifications
15.3 kDa | |
Gly 24 - Ala 155 | |
IL-17 A,Interleukin-17 A,CTLA-8,IL-17 | |
Unconjugated | |
Tag Free | |
Less than 1.0 EU / µg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |
Human IL17A, Tag Free (ILA-H5118) is expressed from E.coli cells. It contains AA Gly 24 - Ala 155 (Accession # Q16552). | |
-20°C | |
IL-17 A | |
Human | |
PBS, pH7.4 | |
E.coli | |
Cytokines and Growth Factors |