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ACROBiosystems Human IL-17 RC Protein, Fc Tag
MALS verified
Brand: ACROBiosystems ILC-H5259-1mg
Additional Details : Weight : 0.00010kg
Description
Interleukin-17 receptor C (IL-17 RC), also known as IL17Rhom, IL-17RL, is the receptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA. IL-17A activity is inhibited by IL-17RA, IL-17F is inhibited by IL-17RC, and a combination of soluble IL-17RA/IL-17RC receptors is required for inhibition of the IL-17F/IL-17A activity. Furthermore, activation of IL17RC can lead to the induction of expression of inflammatory chemokines and cytokines such as CXCL1.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 75.9 kDa. The protein migrates as 90-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Specifications
| NP_703190.2 | |
| 1 mg | |
| Leu 21 - Ala 465 | |
| IL-17 RC,IL-17 RC,IL17Rhom,IL-17 receptor C,IL-17 RL,ZcytoR14 | |
| Unconjugated | |
| Fc Tag | |
| Less than 1.0 EU / µg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 75.9 kDa | |
| Human IL-17 RC, Fc Tag (ILC-H5259) is expressed from human 293 cells (HEK293). It contains AA Leu 21 - Ala 465 (Accession # NP_703190.2). | |
| -20°C | |
| IL-17 RC | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| Bio-Markers and CD Antigens |