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ACROBiosystems Human Fc gamma RIIIB / CD16b (NA2) Protein, SUMO,His Tag (MALS & BLI-verified)

3329.89 NOK - 33298.92 NOK

Specifications

Molecular Weight (g/mol) 33.5 kDa
Source Human CD16b (NA2), SUMO,His Tag (CDB-H5294) is expressed from human 293 cells (HEK293). It contains AA Gly 17 - Ser 200 (Accession # O75015-1).The NA1 form of the CD16b differ with the NA2 form of CD16b in AA36, 65, 82, and 106. The NA1 form carries R36, N65, D82, and V106, while the NA2 form carries S36, S65, N82, and I106.
Immunogen Gly 17 - Ser 200
Storage Requirements -20°C
Gene Alias Fc gamma RIIIB,CD16b (NA2),FCGR3B,CD16B,FCG3B,FCGR3,FCG3,IGFR3
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Products 3
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
17226130
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ACROBiosystems
CDB-H5294-50UG
50 μg
3329.89 NOK
50µg
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Estimated Shipment: 11-04-2024
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17216130
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ACROBiosystems
CDB-H5294-1MG
1 mg
33298.92 NOK
1mg
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17206130
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ACROBiosystems
CDB-H5294-100UG
100 μg
4540.76 NOK
100µg
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Description

Description

CD16 is a low affinity Fc receptor, and has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b). These receptors bind to the Fc portion of IgG antibodies. CD16 encoded by two different highly homologous genes in a cell type-specific manner.CD16 is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages.CD16B is also kown as FCGR3B and FCG3B, is expressed specifically by polymorphonuclear leukocytes (neutrophils) and stimulated eosinophils. CD16B is the low affinity receptor for the Fc region of immunoglobulins gamma. FCGR3B binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, FCG3B is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. CD16B may serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.

This protein carries a SUMO tag at the N-terminus and a polyhistidine tag at the C-terminus. The protein has a calculated MW of 33.5 kDa. The protein migrates as 45-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifications

Specifications

33.5 kDa
Gly 17 - Ser 200
Fc gamma RIIIB,CD16b (NA2),FCGR3B,CD16B,FCG3B,FCGR3,FCG3,IGFR3
Unconjugated
His Tag & SUMO Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE.
Human CD16b (NA2), SUMO,His Tag (CDB-H5294) is expressed from human 293 cells (HEK293). It contains AA Gly 17 - Ser 200 (Accession # O75015-1).The NA1 form of the CD16b differ with the NA2 form of CD16b in AA36, 65, 82, and 106. The NA1 form carries R36, N65, D82, and V106, while the NA2 form carries S36, S65, N82, and I106.
-20°C
Fc gamma RIIIB / CD16b (NA2)
Human
PBS, pH7.4
HEK293
MABSol™ Fc Receptors
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