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ACROBiosystems Human CD209 / DC-SIGN Protein, His Tag

Brand:  ACROBiosystems CD9-H5246-100ug

Additional Details : Weight : 0.00010kg

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Product Code. 16447339

  • 4432.75 NOK / 100µg
Estimated Shipment: 17-01-2023
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Description

Description

CD209 is also known as CLEC4L, DC-SIGN and CD209 antigen. Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. On DCs it is a high affinity receptor for ICAM2 and ICAM3 by binding to mannose-like carbohydrates. May act as a DC rolling receptor that mediates transendothelial migration of DC presursors from blood to tissues by binding endothelial ICAM2. Seems to regulate DC-induced T-cell proliferation by binding to ICAM3 on T-cells in the immunological synapse formed between DC and T-cells.

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 41.3 kDa. The protein migrates as 40-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifications

Specifications

NP_066978.1
41.3 kDa
100 µg
Gln 59 - Ala 404
DC-SIGN,CD209,DC-SIGN1,CLEC4L
Unconjugated
PBS, pH7.4
HEK293
Human
Powder
>90% as determined by SDS-PAGE
Human CD209, His Tag (CD9-H5246) is expressed from human 293 cells (HEK293). It contains AA Gln 59 - Ala 404 (Accession # Q9NN x 6-1).
-20°C
CD209
His Tag
Less than 1.0 EU / µg by the LAL method.
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